Bacterial Vaginosis (BV): Symptoms, Treatment, and Diagnosis in Singapore
Bacterial vaginosis (BV) is the most common vaginal infection in women of reproductive age. It develops when the normal balance of vaginal bacteria shifts: protective Lactobacillus species decrease, and anaerobic bacteria (particularly Gardnerella vaginalis) overgrow. The classic clinical sign is a thin grey-white discharge with a strong fishy odour, especially after sex.
Medically reviewed by Dr. Qiao Yufei, MD
This guide covers what BV is, the Amsel diagnostic criteria, metronidazole treatment, why recurrence is so common, and pregnancy implications. BV pairs clinically with trichomoniasis (similar fishy odour) and candidiasis (yeast infection, the differential diagnosis). It is one of several conditions covered in our broader STDs in Singapore overview.
What is bacterial vaginosis?
Bacterial vaginosis is a vaginal microbiome imbalance rather than a single-pathogen infection. The healthy vagina is dominated by Lactobacillus species that produce lactic acid, keep the vaginal pH below 4.5, and protect against pathogens. In BV, this balance is disrupted: Lactobacillus decreases, vaginal pH rises, and anaerobic bacteria including Gardnerella vaginalis, Atopobium vaginae, Mobiluncus, and Prevotella overgrow.
According to the US Centers for Disease Control and Prevention (CDC), BV affects roughly 1 in 3 women aged 15 to 44 in the US, making it the most common vaginal infection in this age group. Singapore prevalence is similar.
No, not in the strict sense. Women who have never been sexually active can still develop BV, and unlike chlamydia or gonorrhoea, BV is not transmitted from a single infected partner. However, BV is sexually associated: new or multiple partners, unprotected sex, and douching all disrupt the vaginal microbiome and increase risk.
What triggers bacterial vaginosis?
Anything that disrupts the vaginal microbiome can tip the balance towards BV. Common contributors include:
- New or multiple sexual partners (the strongest risk factor)
- Unprotected sex: semen is alkaline and changes vaginal pH
- Douching or vaginal washing: disrupts the protective Lactobacillus environment
- Scented products (soaps, bubble baths, vaginal deodorants)
- Antibiotic use for unrelated infections, which can disturb vaginal flora
- Hormonal changes (menstruation, pregnancy, menopause)
- Smoking: associated with reduced Lactobacillus species
- Intrauterine devices (IUDs): small association with BV recurrence
BV is NOT caused by
- Toilet seats, swimming pools, or shared bathrooms
- Poor general hygiene (in fact, over-washing makes it worse)
- Wearing tampons or pads
- Casual contact with another person
Signs and symptoms of bacterial vaginosis
About half of women with BV have no symptoms at all. When symptoms occur, they are typically distinctive:
Classic BV symptoms
- Thin, grey-white vaginal discharge
- Strong fishy odour, especially after sex
- Mild vaginal itching or burning
- Discomfort during urination (less common)
- Discharge often coats the vaginal walls evenly
How BV differs from look-alikes
- BV vs candidiasis (thrush): thrush has thick white "cottage cheese" discharge, NO fishy smell, intense itching
- BV vs trichomoniasis: trich has frothy yellow-green discharge, strong fishy smell PLUS irritation, often genital pain
- BV vs healthy discharge: BV pH > 4.5; healthy discharge is pH 3.8–4.5 with no fishy odour
Consider testing for chlamydia, gonorrhoea, or trichomoniasis simultaneously: these can co-occur with BV, and symptoms overlap. Routine screening is also reasonable for any new vaginal symptoms in sexually active women.
How BV is diagnosed: the Amsel criteria
BV is diagnosed clinically using the Amsel criteria: at least 3 of 4 must be present for a diagnosis of BV.
Thin, homogeneous, grey-white discharge
Coats the vaginal walls evenly, unlike the curd-like discharge of yeast.
Vaginal pH greater than 4.5
Tested with a pH strip on a sample of vaginal fluid. Normal vaginal pH is 3.8–4.5.
Positive "whiff test"
Adding 10% potassium hydroxide (KOH) to a sample releases a strong fishy amine smell.
Clue cells on microscopy
Vaginal epithelial cells coated with bacteria, giving them a stippled "fuzzy" border under the microscope.
Lab gold standard: Nugent score
For research and difficult cases, the lab gold standard is Nugent scoring on Gram stain: a numerical score (0–10) based on relative quantities of Lactobacillus, Gardnerella/Bacteroides, and Mobiluncus morphotypes. A score of 7 or higher = BV.
NAAT testing
Modern NAAT panels (such as Affirm VPIII or BD MAX Vaginal Panel) can detect Gardnerella, Atopobium, and Megasphaera together with simultaneous detection of trichomonas and yeast, providing a definitive lab diagnosis. At Mediway Medical Centre, the standard initial assessment uses Amsel criteria with reflex NAAT for unclear cases.
Bacterial vaginosis treatment
BV is treated with antibiotics that target the overgrowth of anaerobic bacteria. Several options are equally effective; choice depends on patient preference, pregnancy status, and prior recurrence:
- Metronidazole 500 mg orally twice daily for 7 days (current first-line per CDC)
- Metronidazole 0.75% vaginal gel once daily for 5 days (avoids systemic side effects, including alcohol intolerance)
- Clindamycin 2% vaginal cream once daily for 7 days (alternative; weakens latex condoms)
- Tinidazole orally for 2–5 days (alternative; fewer GI side effects than metronidazole)
- Secnidazole single oral 2 g dose (newer single-dose option)
Important: avoid alcohol
Oral metronidazole and tinidazole interact with alcohol, causing a disulfiram-like reaction (severe nausea, vomiting, headache). Avoid alcohol during treatment and for at least 24 hours after metronidazole, or 72 hours after tinidazole. Vaginal preparations (gel, cream) carry less alcohol risk but caution is still recommended.
Partner treatment
Routine treatment of male partners is not currently recommended: BV is not transmitted as a single-pathogen STI, and partner treatment has not been shown to reduce recurrence in trials. However, in same-sex female partners, both may benefit from concurrent treatment because they share vaginal microbiomes.
Why does BV keep coming back?
Recurrence is the most challenging aspect of BV. About 50% of women treated for BV develop recurrence within 12 months. The underlying issue: antibiotics kill the overgrown anaerobes but do not always restore the protective Lactobacillus community.
Strategies for recurrent BV
- Suppressive metronidazole gel twice weekly for 4 to 6 months: the standard maintenance regimen for frequent recurrence
- Lifestyle changes: stop douching, avoid scented products, use unscented mild soap externally only, wear cotton underwear, limit unprotected sex with new partners
- Probiotic adjuncts: oral or vaginal Lactobacillus probiotics may help restore microbiome (evidence mixed, but generally safe to try)
- Reassess differential: persistent symptoms despite treatment may signal trichomoniasis, mycoplasma, or aerobic vaginitis
- Vaginal microbiome transplant (VMT): an experimental approach being studied for treatment-resistant BV
How to reduce BV risk
Protect the vaginal microbiome
- Do not douche: this is the strongest single protective measure
- Avoid vaginal deodorants, scented bath products, and harsh soaps near the vagina
- Use mild, unscented soap externally only; never inside the vagina
- Wear breathable cotton underwear and change out of damp clothes promptly (Singapore humidity is a real factor)
Reduce sexual risk factors
- Use condoms consistently to reduce semen exposure (semen is alkaline and disrupts vaginal pH)
- Limit the number of sexual partners
- Clean sex toys thoroughly between uses
Get screened if symptoms recur
Recurrent vaginal symptoms warrant medical assessment. Your doctor can confirm BV with Amsel criteria, exclude other causes (yeast, trichomoniasis, chlamydia, gonorrhoea), and discuss suppressive treatment options if needed.
What happens if BV is left untreated?
Many BV cases resolve spontaneously without treatment, but untreated symptomatic or recurrent BV can cause:
- Persistent vaginal discomfort with chronic discharge and odour
- Increased STI acquisition risk: BV doubles the risk of acquiring chlamydia, gonorrhoea, herpes, HIV, and trichomoniasis
- Pregnancy complications: preterm labour, premature rupture of membranes, low birth weight, postpartum endometritis
- Pelvic inflammatory disease (PID): less common than with chlamydia or gonorrhoea, but BV-associated PID is recognised
- Post-procedure infection: BV increases risk of infection after gynaecological procedures (hysterectomy, IUD insertion, surgical abortion)
BV is straightforward to treat with antibiotics. The main challenge is preventing recurrence: lifestyle changes plus, where needed, suppressive maintenance therapy.
Frequently asked questions
01 What is bacterial vaginosis (BV)?
Bacterial vaginosis (BV) is a common vaginal condition caused by an imbalance of the natural bacteria in the vagina. Normally the vagina is dominated by Lactobacillus bacteria. In BV, these protective bacteria are reduced and other bacteria (commonly Gardnerella vaginalis and others) overgrow. BV is the most common cause of unusual vaginal discharge in women of reproductive age. Many women with BV have no symptoms.
02 What causes BV?
BV develops when the natural balance of vaginal bacteria is disrupted. Common triggers include sexual activity (especially with new or multiple partners), douching or vaginal washing with harsh products, hormonal changes, and antibiotic use. The exact cause is not fully understood, and BV can occur in women who are not sexually active. BV is not caused by poor hygiene.
03 What are the symptoms of BV?
Many women with BV have no symptoms. When symptoms occur, the most common is thin, grey or white vaginal discharge with a fishy odour, often more noticeable after sex or during periods. Some women also experience vaginal itching or burning during urination. Pain is uncommon. BV symptoms can overlap with yeast infection or trichomoniasis, so testing helps confirm the diagnosis.
04 Is BV an STI?
BV is not classified as a sexually transmitted infection, but sexual activity can influence BV risk. New or multiple partners, douching, and unprotected sex can disrupt the vaginal microbiome. BV can also occur in women who are not sexually active. Male partners do not typically need treatment, but female partners of women with BV may benefit from evaluation in some cases.
05 Is BV curable?
Yes. BV is curable with appropriate antibiotic treatment prescribed by a doctor. Most cases respond well to a short course. However, BV can recur after treatment, and recurrence within a year is common. Recurrent BV may require longer courses or maintenance treatment. Identifying and addressing triggers can help reduce recurrence.
06 How is BV treated?
BV is treated with prescription antibiotics. Your doctor will choose the appropriate antibiotic and form (oral tablet, vaginal cream, vaginal gel) based on your situation, pregnancy status, allergies, and current clinical guidance. Complete the prescribed course even if symptoms improve. Avoid alcohol with certain BV medications if advised by your doctor.
07 How can I prevent BV?
BV risk can be reduced by avoiding douching or vaginal washing with harsh products, using mild unscented soap externally only, wearing breathable cotton underwear, changing out of damp swimwear or workout clothes promptly, using condoms (which may help reduce risk especially with new partners), and limiting unnecessary antibiotic use. There is no proven way to fully prevent BV.
08 What happens if BV is left untreated?
Many BV episodes may improve, but symptomatic or persistent BV should be assessed and treated. In pregnancy, untreated BV has been associated with preterm delivery, low birthweight, and post-delivery infection. Untreated BV may also increase the risk of acquiring other STIs (including HIV) and may contribute to pelvic inflammatory disease (PID) in some cases.
09 Why does BV keep coming back?
Recurrent BV is common, with recurrence within a year of treatment occurring in many women. Triggers may include resumption of sexual activity with the same untreated partner, ongoing douching, antibiotic use, hormonal changes, or persistent shifts in vaginal flora. A doctor can recommend longer treatment courses or maintenance therapy and help identify contributing factors.
10 Where can I get tested or treated for BV in Singapore?
You can be assessed at Mediway through a GP consultation. Diagnosis may include symptoms, examination, vaginal pH, microscopy, or a vaginal swab, depending on the clinical situation (the Amsel criteria are commonly used). The doctor will recommend appropriate treatment based on the diagnosis and your situation. Speak to our team to arrange a confidential consultation.
Related conditions and next steps
References: CDC: BV treatment guidelines · WHO: STIs fact sheet · HealthHub Singapore
This page is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Consult a qualified healthcare professional for diagnosis and treatment of suspected bacterial vaginosis.