Pre-Vaccination Screening
Confirm whether you actually need MMR, Hep B, or varicella before paying for vaccines.
- Measles, Mumps, Rubella IgG
- Varicella IgG
- Hep B anti-HBs
From $220(estimated)
Book panel
Know what your immune system has seen. Antibody and antigen blood panels in three categories: vaccine immunity, infection screening, and autoimmune. HSA-registered platforms, results in 1 to 3 working days.
Medically reviewed by Dr. Qiao Yufei, MD
A serology test is a blood test that measures antibodies in your serum to confirm immunity to vaccine-preventable diseases, screen for current or past infection, or evaluate suspected autoimmune disease.
A blood-based laboratory test that measures specific antibodies (or in some cases antigens) in your serum, used to determine immunity status, diagnose recent or past infection, and evaluate certain autoimmune conditions.
Serology measures the antibodies (immunoglobulins) your body produces in response to infection or vaccination. IgM antibodies appear first (typically days 4 to 14), indicating recent or active immune response. IgG antibodies follow (from week 2 onwards) and persist for years or for life, indicating long-term memory and immunity.
Serology versus PCR versus antigen tests: serology detects your antibody response to a pathogen. PCR detects the pathogen’s genetic material directly (most useful for diagnosing current infection). Antigen tests detect pathogen proteins (commonly used for rapid diagnosis). Each answers a different clinical question.
At Mediway, samples are processed on HSA-registered immunoassay platforms (CLIA or ELISA) at an accredited Singapore reference laboratory. Standard turnaround is 1 to 3 working days.
All tests organised by the clinical question they answer. Tap a category to view the available tests.
Measles, mumps and rubella antibody panel from $120. Accepted by MOM for migrant domestic worker measles immunity (June 2025 ruling).
Quantitative anti-HBs surface antibody titre to confirm vaccine-induced or post-infection immunity. Often required for healthcare workers and students.
VZV IgG to confirm chickenpox immunity from past infection or vaccination. Required for many childcare and healthcare pre-employment screens.
Anti-HAV IgG to confirm immunity for travel to endemic regions or food-handler pre-employment.
Confirms prior dengue infection. Required pre-screening for Dengvaxia eligibility (the dengue vaccine is only recommended in seropositive patients aged 12 to 45).
Third-generation anti-HCV antibody screen. Reactive results trigger reflex HCV RNA confirmation.
For diagnosis during acute fever (within 7 days of onset). NS1 antigen plus dengue IgM antibody.
Fourth-generation HIV Ag/Ab combination test, plus anonymous and rapid options. See our dedicated HIV testing page.
Treponemal antibody, RPR, and HSV-1 / HSV-2 type-specific IgG. Covered in our STD testing cluster.
Autoimmune testing is rarely useful as a standalone screen. We assess your symptoms and history before ordering markers, and refer to a rheumatologist when results suggest active disease.
Four use-case bundles built around common Singapore scenarios. One blood draw covers everything in the panel.
Confirm whether you actually need MMR, Hep B, or varicella before paying for vaccines.
Immunity check before travelling to regions with active measles, hepatitis A or hepatitis B transmission.
Pre-employment titres typically required by hospital, clinic, preschool and childcare HR.
Pre-pregnancy immunity check, often combined with our premarital screening package.
Most serology reports return a combination of IgG and IgM results. The matrix below shows the four common patterns and what each typically means.
Lasting protection from past infection or vaccination. Usually no further action.
e.g. anti-HBs ≥ 10 mIU/mL, measles IgG ≥ 16.5 AU/mLActive or recent immune response. Clinical correlation required.
Notifiable diseases (e.g. measles) require IDA reportingNo detectable antibodies. Vaccination usually advised.
Rubella IgG < 10 IU/mL = consider catch-up MMREarly antibody response, IgG not yet developed. Repeat in 2 to 4 weeks.
Window-period varies by pathogenFalse negatives can occur during seroconversion (the gap between exposure and detectable antibodies, typically 1 to 4 weeks). Antibody titres can also wane over time. A positive IgG cannot reliably distinguish post-vaccine immunity from natural-infection immunity. We interpret every result alongside your clinical history.
Five common situations where a serology blood test is the right answer.
If you might already be immune (childhood vaccines, prior infection), serology can save the cost of unnecessary doses.
Hep A immunity for travel to South Asia, measles immunity given current outbreaks, dengue IgG before considering Dengvaxia.
Hospitals, clinics, preschools and food-handler roles often require documented immunity. Universities may also request titres on entry.
Rubella IgG, Hep B HBsAg + anti-HBs, HIV and syphilis are routine. Knowing your immunity status helps plan a safer pregnancy.
Fever with rash, persistent fatigue, joint pains or chronic abnormal liver function may prompt targeted serology alongside other tests.
A typical visit takes about 15 minutes for the blood draw, plus the lab turnaround.
Doctor reviews your reason for testing, vaccination history and symptoms. Confirms which tests are appropriate.
~5 minApproximately 5 to 10 ml of venous blood drawn into appropriate tubes by a trained nurse.
~5 minSample sent to an accredited Singapore reference laboratory. Antibodies measured by chemiluminescent immunoassay (CLIA), ELISA, or indirect immunofluorescence.
1 to 3 daysDigital report sent by email for most tests. Our doctor reviews the result and advises on next steps.
By emailIncludes MMR Serology Panel, Hep B Immunity, Varicella IgG, Hep A IgG, Dengue IgG and Hep C antibody. Eat normally before your appointment and stay well hydrated to make the blood draw easier.
SST + EDTA · ~7 ml · Same to next working day given clinical urgency.
SST + EDTA · ~10 ml · 2 to 5 working days for multi-marker processing.
Transparent SGD pricing across all eight tests, plus four curated panels for common scenarios.
* Prices marked with asterisk are estimated, pending clinic confirmation. All prices GST-inclusive and subject to change depending on individual clinical needs. MediSave and most private insurance plans do not routinely cover serology screening unless ordered for a specific medical indication. Please contact us for the latest pricing.
Common questions about serology testing in Singapore. For anything specific to your situation, please speak with our doctor.
Single serology tests at Mediway start from around $40 (Hep B anti-HBs alone), with most individual antibody tests in the $55 to $80 range. The MMR full panel is $120. Curated bundles for common scenarios (Pre-Vax, Travel, HCW, Pregnancy) start from $200. All prices are GST-inclusive and may vary depending on clinical needs.
Serology tests measure specific antibodies in your blood to answer one of three clinical questions: (1) am I immune to a disease I have been vaccinated for? (2) do I have a current or past infection? (3) is there evidence of an autoimmune condition? Different antibodies (IgG, IgM, IgA) and patterns help distinguish these answers.
Serology detects your antibody response to an infection or vaccine. PCR detects the pathogen’s genetic material directly (most useful in active infection, e.g. swab tests). Antigen tests detect proteins on the pathogen surface (rapid tests, also for active infection). Serology is most useful for immunity confirmation and past infection; PCR and antigen tests are most useful for diagnosing current infection.
Most serology tests at Mediway return within 1 to 3 working days. Acute dengue (NS1 + IgM) is often available same or next working day given clinical urgency. Autoimmune panels typically take 2 to 5 working days due to multi-marker processing. The MMR panel offers an optional same-day 4pm report for an additional $15 when blood is drawn before the morning cut-off.
No, fasting is not required for serology testing. Eat normally and stay well hydrated before your appointment. Hydration makes the blood draw more comfortable. If your serology is being combined with other tests (e.g. a fasting cholesterol panel), the doctor will advise on fasting requirements at booking.
MediSave does not routinely cover screening serology done at the patient’s request. Coverage may apply when serology is part of a broader medical workup ordered for a specific indication. Most private insurance and corporate health plans cover serology when documented as medically necessary; check your policy or speak with our admin team for help with claims.
For migrant domestic workers (MDWs), MOM’s June 2025 ruling requires evidence of measles immunity (vaccination record OR positive measles IgG OR completed MMR vaccination at a Singapore GP clinic). For work pass medical examinations, HIV, syphilis and Hepatitis B serology are commonly required, alongside chest X-ray. See our Work Permit medical, 6ME / FDW medical and pre-employment medical pages for the full required panel.
The standard antenatal serology profile in Singapore typically includes: Hepatitis B surface antigen (HBsAg), syphilis (RPR or treponemal antibody), HIV (Ag/Ab combination), and rubella IgG to confirm rubella immunity (since rubella infection during pregnancy can cause foetal harm). Many clinics also include varicella IgG and Hep B anti-HBs. See our premarital screening page for combined panels.
Most antibody titres develop fully 4 to 8 weeks after the final vaccine dose. For Hep B, a post-vaccination anti-HBs titre is typically taken 1 to 2 months after completing the 3-dose series. For MMR, varicella and Hep A, immunity check is usually performed at least 4 to 6 weeks after the second dose. Earlier testing risks a false-negative result.
Dengvaxia (CYD-TDV) is HSA-registered for individuals aged 12 to 45 years with documented past dengue infection. Vaccination of dengue-naive individuals is contraindicated because of the risk of antibody-dependent enhancement on subsequent natural infection. A dengue IgG serology test is therefore the standard pre-vaccination screen. Eligibility decisions involve other factors as well; consult a clinician for individual assessment.
Two ways to start. Book ahead to reserve a time, or walk in during operating hours.
Reserve a slot through our online booking. Confirmation by email or WhatsApp.
Book Serology TestMon to Fri 7:30am to 6pm, Sat 7:30am to 1pm. Sundays and public holidays closed.
WhatsApp 8779 9898Pages elsewhere in our cluster that pair naturally with serology testing.
Four-test measles, mumps and rubella antibody panel from $120, with optional same-day reporting.
View test VaccinesAdult and travel vaccinations including MMR, Hepatitis B, Hepatitis A, varicella and influenza.
View vaccines ScreenFourth-generation HIV Ag/Ab combination test, anonymous and rapid options. Confidential.
View HIV test ScreenTargeted and full STD panels including syphilis, HSV, gonorrhoea, chlamydia and Hepatitis B.
View STD tests ScreenComprehensive health screening packages combining serology with cardiovascular, metabolic and cancer markers.
View packages ScreenCombined immunity and infection panel for couples planning pregnancy. Includes rubella IgG, Hep B, HIV, syphilis.
View screeningSources cited on this page.